Neuroscience
Neuroscience Research Group
Research areas include:
- morphological basis of neural plasticity and learning in the mammalian CNS.
- molecular biology of learning; gene activation in memory formation.
- biochemical basis of learning and memory in the chick.
- electrophysiological studies of the synaptic and cellular basisof learning and memory deficits in neurodegenerative disease (current focus on Huntingdon's disease) histological markers of neurodegnerative changes in diseased brain
- use of flash photolysis of caged-compounds to unravel the dynamic molecular events that subserve learning and memory in the mammalian brain.
- behavioural models for exploring memory formation.
- the relative physiological efficacies of delta and mu opiate agonists.
- the central control of movement.
- development and ageing of the mammalian enteric nervous system (link).
- tissue engineered repair of peripheral nerves and the spinal cord.
- 3-dimensional cell culture modelling of the nervous system damage and repair environment.
- exploring Alzheimer’s disease.
- neural networks and synaptic circuits in the prefrontal cortex and related brain areas.
- anatomical connectionist modelling of the cerebral cortex.
- normal and abnormal development of the human and rodent brain.
- neuropathology of neurological and neuropsychiatric conditions, including autism.