Neuroscience of Attention
The Neuroscience of Attention research encompasses the work of
Dr Claire Rostron and
Dr Ellie Dommett and falls into two broad areas. The first, led by Dr Rostron focuses on the neural basis of attention, specifically defining the role of the cholinergic neurons in the Pedunculopontine Tegmental Nucleus (PPTg) , in contrast to the role of cholinergic neurons in the Nucleus Basalis of Meynert in cognitive function. Current research is directed towards understanding the role of the PPTg in orienting of attention using the covert orienting task (COVAT) as well as developing a rodent version of the endogenous cueing form of the COVAT and investigating the methodological parameters required for observing inhibition of return in the rat.
The second area within this research theme is led by
Dr Dommett and investigates the neural basis of deficits in attention, specifically those found in Attention Deficit Hyperactivity Disorder. This disorder affects an estimated 10% of children worldwide and in around 60% of sufferers it will continue into adulthood. Despite this high prevalence little is known about the neuropathology of ADHD or the mechanisms of action that make drugs such as methylphenidate (Ritalin, Concerta) efficacious. The aim of the research therefore is to investigate how and where these drugs might be effective, thus shedding light on the neuropathology of the disorder and potentially opening avenues of development for drug treatments. The work uses both behavioural and electrophysiological techniques.
Links to:
Dr Claire Rostron
Dr Ellie Dommett
Ulf Wagner (PhD Student)
