Thursday 30 May 2013
08.00 Registration, coffee and pastries
09.10 Welcome and introduction - Dr Payam Rezaie, The Open University
Opening Session
09.20 Prof Steven Rose, The Open University
09.30 Dr Doug Brown, Director of Research & Development, Alzheimer’s Society
09.40 Dr Eric Karran, Director of Research, Alzheimer’s Research UK
Session 1: Global Perspectives - The Impact of Dementia
Chair: Prof Steven Rose
09.50 Prof Martin Prince, Institute of Psychiatry, King’s College London
The global burden of dementia (focus on epidemiology and risk factors)
10.30 Prof Sube Banerjee, Brighton and Sussex Medical School
Quality of life and the impact of dementia (focus on social and cultural aspects)
Session 2: Diagnosis and Assessment
Chair: Prof Martin Prince
11.10 Dr Peter Bowie, Sheffield Health & Social Care NHS Foundation Trust
Differential diagnosis and clinical assessment of the dementias (including changes introduced in DSM-V)
11.50 Prof Robin Morris, Institute of Psychiatry, King’s College London
Neuropsychological assessment of dementia
12.30 Lunch
Session 3: Genetics and Neurobiology 1
Chair: Prof Sube Banerjee
13.30 Prof Julie Williams, University of Cardiff
Identifying and understanding genes which increase the risk of developing Alzheimer’s disease and other dementias
14.10 Prof Stephen Gentlemen, Imperial College London
Molecular pathogenesis and neuropathology of Alzheimer’s disease (biology of A-beta, NFTs and their roles in AD pathogenesis)
14.50 Prof Paul Francis, King’s College London, University of London
Neurochemistry of Alzheimer’s disease and other dementias (neurochemical systems involved in learning and memory)
15.30 Coffee
UK Research Highlights Session A (Recent Findings, New and Emerging Areas)
Panel: Professors Julie Williams, Paul Francis and Dr Peter Bowie
16.00 Prof Michael Stewart, The Open University
Synaptic plasticity in learning and memory – EU Framework ‘PROMEMORIA’ and ‘MEMSTICK’ projects
16.15 Dr Rita Guerreiro, UCL Institute of Neurology
New risk gene (TREM2 variant) suggests immune response plays a key role in AD
16.30 Dr Roxana Carare, University of Southampton
A role for the susceptibility gene APOE in AD – linking APOE e4 to clearance of beta amyloid
16.45 Dr Christopher Kobylecki, University of Manchester
Amyloid imaging of AD versus FTD
17.00 Dr Josephine Barnes, UCL Institute of Neurology
Predicting brain atrophy in AD – white matter disease and CSF markers of AD pathology
17.15 Professor Margaret Esiri, University of Oxford
Cognitive reserve, cortical plasticity and resistance to Alzheimer’s disease
17.30 Dr Ilona Roth, The Open University
A comprehensive profile of awareness in early stage dementia – the MIDAS project
17.45 Symposium discussion (Day 1) led by panel and session chairs
18.00 Close of meeting (Day 1)
18.00 Social Event - Wine Reception (Venue: Berrill Ground Floor, Open University)
19.00 Symposium Dinner Guest Speaker: Baroness Susan Greenfield CBE
The challenges and impact of dementia research
Friday 31 May 2013
08.30 Registration
Session 4: Genetics and Neurobiology 2
Chair: Dr Payam Rezaie
09.00 Prof Stuart Pickering-Brown, University of Manchester
Frontotemporal dementia: clinical characteristics, diagnosis, genetics and molecular pathology
09.40 Prof Johannes Attems, University of Newcastle
Dementia with Lewy bodies: insights into pathology, pathogenesis and treatment
10.15 Coffee
Session 5: Interventions 1
Chair: Prof Clive Holmes
10.40 Prof John Zajicek, Peninsula Colleges of Medicine and Dentistry, University of Plymouth
Clinical trials in dementia - the evidence base for treatment of the dementias
11.20 Prof Gordon Wilcock, University of Oxford
Established and emerging pharmacotherapy for the treatment and prevention of dementia
12.00 Dr Eric Karran, Alzheimer’s Research UK
The amyloid cascade hypothesis for Alzheimer’s disease: an appraisal for the development of therapeutics (latest developments and future research)
12.40 Lunch
Session 6: Interventions 2
Chair: Prof Gordon Wilcock
13.30 Prof Clive Holmes, University of Southampton
The biological and clinical outcomes of immunotherapy and the role of inflammation in the development of Alzheimer’s disease
14.10 Prof Martin Orrell, UCL Mental Health Sciences Unit, University of London
Cognitive stimulation therapy and psychosocial interventions for dementia
14.50 Prof Jan Oyebode, University of Bradford
Management of dementia – innovations in care and support
15.30 Coffee
UK Research Highlights Session B (Recent Findings, New and Emerging Areas)
Panel: Professors John Zajicek, Martin Orrell and Johannes Attems
16.00 Dr Naheed Mukadam, UCL Mental Health Sciences Unit
The experience of dementia across ethnic groups - improving access to services
16.15 Dr Sebastian Crutch, UCL Institute of Neurology
Investigating posterior cortical atrophy
16.30 Prof Kevin Morgan, University of Nottingham
Biomarkers as clues to early AD diagnosis – a panel approach
16.45 Dr Magdalena Sastre, Imperial College London
Investigating the link between AD and type 2 diabetes
17.00 Dr Ruth Peters, Imperial College London
Blood pressure, smoking and alcohol use – association with vascular dementia
17.15 Dr Atticus Hainsworth, St George’s, University of London
Experimental models of vascular dementia
17.30 Symposium discussion (Day 2) led by panel and session chairs
17.45 Closing Speaker Prof. Michael Stewart, The Open University
18.00 Close of Meeting (Day 2)