{"id":5497,"date":"2017-05-10T14:53:00","date_gmt":"2017-05-10T13:53:00","guid":{"rendered":"https:\/\/ounews.co\/?p=5497"},"modified":"2017-05-10T14:53:00","modified_gmt":"2017-05-10T13:53:00","slug":"could-painkillers-increase-risk-heart-attack","status":"publish","type":"post","link":"https:\/\/www.open.ac.uk\/blogs\/news\/education-languages-health\/health\/could-painkillers-increase-risk-heart-attack\/","title":{"rendered":"“Could painkillers increase our risk of a heart attack?” OU academic explains"},"content":{"rendered":"

Research by the University of Montreal Hospital Research Centre<\/a>, published in The British Medical Journal (BMJ)<\/a>, suggests that\u00a0nonsteroidal anti-inflammatory drug (NSAID) painkillers could increase the risk of heart attacks. The study of five NSAID painkillers, including ibuprofen, concluded that the risk of suffering from a heart attack was as much as 50% greater in those using the drugs compared to those that are not.<\/p>\n

So should we be concerned? Emeritus Professor of Applied Statistics, Kevin McConway<\/a>, has deciphered the figures and explains more.<\/p>\n

What type of study is this?<\/strong><\/h2>\n

“This is an observational study, which means that conclusions cannot be made about cause and effect. That\u2019s because the researchers couldn\u2019t take into account all the factors that might influence both the prescribing of painkillers \u00a0and the chance of a heart attack, usually because they did not have adequate data on them. The research report mentions several such factors \u2013 smoking, obesity, income, education, and taking painkillers bought over the counter (and so not recorded in the data). So, for instance, perhaps people who smoke are more likely to be prescribed painkillers, and are separately more likely to have a heart attack.<\/p>\n

“Or, putting it crudely, if someone is prescribed a high dose of a painkiller because of severe pain, and then has a heart attack in the following week, it\u2019s pretty hard to tell whether the heart attack was caused by the painkiller or by whatever was the reason for prescribing the pain killer (or indeed by something else entirely).”<\/p>\n

Will painkillers really increase my risk of a heart attack?<\/h2>\n

“In the UK, according to the British Heart Foundation<\/a>, there were about 190,000 hospital visits due to heart attacks in 2015.<\/p>\n

“It\u2019s true the researchers conclude there is\u00a0a chance of over 90% that each of the painkillers is associated with an increased heart attack risk; but that says nothing about the size of the increase. A very tiny increase in risk probably doesn\u2019t matter. It also means that there is a chance, albeit a fairly small one (less than 10%), that painkiller use actually decreases the heart attack risk.”<\/p>\n

Should we be worried about taking painkillers?<\/h2>\n

“Although this new study has helped persuade me that there\u00a0is probably a real association between taking these painkillers and heart attacks, some aspects do still remain pretty unclear. It is\u00a0possible that the painkillers aren\u2019t actually the cause of the extra heart attacks, and there\u2019s still a lot of uncertainty about the strength of the relationships and about how they vary with dose and with the timing of taking the painkillers.<\/p>\n

We have\u00a0to remember that all drugs have side effects, and that people aren\u2019t prescribed these painkillers for fun, but to deal with a real pain problem.<\/p><\/blockquote>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Research by the University of Montreal Hospital Research Centre, published in The British Medical Journal (BMJ), suggests that\u00a0nonsteroidal anti-inflammatory drug (NSAID) painkillers could increase the risk of heart attacks. The study of five NSAID painkillers, including ibuprofen, concluded that the risk of suffering from a heart attack was as much as 50% greater in those […]<\/p>\n","protected":false},"author":6,"featured_media":5507,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[1042,1409,1658,1810,2113],"class_list":["post-5497","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-health","tag-medicine","tag-painkilliers","tag-professor-kevin-mcconway","tag-statistics"],"_links":{"self":[{"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/posts\/5497","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/comments?post=5497"}],"version-history":[{"count":0,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/posts\/5497\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/media\/5507"}],"wp:attachment":[{"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/media?parent=5497"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/categories?post=5497"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.open.ac.uk\/blogs\/news\/wp-json\/wp\/v2\/tags?post=5497"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}