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Dr Colette Christiansen

Profile summary

Professional biography

I am a Staff Tutor in the School of Mathematics and Statistics and I have been teaching statistics at the Open University since 2019.  I have a PhD in Epigenetics from King's College London. Prior to moving into academia I was a consulting actuary.

Research interests

My research interests are in applying mathematics and statistics to biology, particularly in the field of genetics and epigenetics.  I chair the Mathematical Biology research group and I am keen to promote interdisciplinary working.  I am currently a Deputy Lead for the Open Societal Challenges research programme.

Teaching interests

My teaching interests are in statistics.  I currently teach M249 "Practical Modern Statistics" and have previously taught M140 "Introduction to Statistics".  In addition I am Deputy Chair for M348 "Applied Statistical Modelling".


Enhanced resolution profiling in twins reveals differential methylation signatures of type 2 diabetes with links to its complications (2024-05)
Christiansen, Colette; Potier, Louis; Martin, Tiphaine C.; Villicaña, Sergio; Castillo-Fernandez, Juan E.; Mangino, Massimo; Menni, Cristina; Tsai, Pei-Chien; Campbell, Purdey J.; Mullin, Shelby; Ordoñana, Juan R.; Monteagudo, Olga; Sachdev, Perminder S.; Mather, Karen A.; Trollor, Julian N.; Pietilainen, Kirsi H.; Ollikainen, Miina; Dalgård, Christine; Kyvik, Kirsten; Christensen, Kaare; van Dongen, Jenny; Willemsen, Gonneke; Boomsma, Dorret I.; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Wilson, Scott G.; Grundberg, Elin; Spector, Tim D. and Bell, Jordana T.
EBioMedicine, 103, Article 105096

Stratified genome-wide association analysis of type 2 diabetes reveals subgroups with genetic and environmental heterogeneity (2023-08-15)
Christiansen, Colette E.; Arathimos, Ryan; Pain, Oliver; Molokhia, Mariam; Bell, Jordana T. and Lewis, Cathryn M.
Human Molecular Genetics, 32, Article ddad093(16)

Accelerated epigenetic aging and DNA methylation alterations in Berardinelli-Seip congenital lipodystrophy (2023-06-01)
Qannan, A; Bejaoui, Y; Izadi, M; Yousri, N; Razzaq, A; Christiansen, C; Martin, G; Bell, J; Horvath, S; Oshima, J; Megarbane, A; Ericson, J; Pourkarimi, E and Hajj, N
Human Molecular Genetics, 32(11) (pp. 1826-1835)

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes (2023-05)
McAllan, Liam; Baranasic, Damir; Villicaña, Sergio; Brown, Scarlett; Zhang, Weihua; Lehne, Benjamin; Adamo, Marco; Jenkinson, Andrew; Elkalaawy, Mohamed; Mohammadi, Borzoueh; Hashemi, Majid; Fernandes, Nadia; Lambie, Nathalie; Williams, Richard; Christiansen, Colette; Yang, Youwen; Zudina, Liudmila; Lagou, Vasiliki; Tan, Sili; Castillo-Fernandez, Juan; King, James W. D.; Soong, Richie; Elliott, Paul; Scott, James; Prokopenko, Inga; Cebola, Inês; Loh, Marie; Lenhard, Boris; Batterham, Rachel L.; Bell, Jordana T.; Chambers, John C.; Kooner, Jaspal S. and Scott, William R.
Nature Communications, 14, Article 2784

Genetic Impacts on DNA methylation help elucidate regulatory genomic processes (2023)
Villicana, Sergio; Castillo-Fernandez, Juan; Hannon, Ellis; Christiansen, Colette; Tsai, Pei-Chen; Maddock, Jane; Kuh, Diana; Suderman, Matthew; Power, Christine; Relton, Caroline; Ploubidis, George; Wong, Andrew; Hardy, Rebecca; Goodman, Alissa; Ong, Ken and Bell, Jordana
Genome Biology, 24, Article 176(1)

A faecal metabolite signature of impaired fasting glucose: results from two independent population-based cohorts (2023)
Nogal, Ana; Tettamanzi, Francesca; Dong, Qiuling; Louca, Panayiotis; Visconti, Alessia; Christiansen, Colette; Breuninger, Taylor; Linseisen, Jakob; Grallert, Harald; Wawro, Nina; Asnicar, Francesco; Wong, Kari; Baleanu, Andrei-Florin; Michelotti, Gregory A.; Segata, Nicola; Falchi, Mario; Peters, Annette; Franks, Paul W.; Bagnardi, Vincenzo; Spector, Tim D; Bell, Jordana T; Gieger, Christian; Valdes, Ana M and Menni, Cristina
Diabetes Care, 72(12) (pp. 1870-1880)

Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers (2022)
Christiansen, Colette; Tomlinson, Max; Eliot, Melissa; Nilsson, Emma; Costeira, Ricardo; Xia, Yujing; Villicaña, Sergio; Mompeo, Olatz; Wells, Philippa; Castillo-Fernandez, Juan; Potier, Louis; Vohl, Marie-Claude; Tchernof, Andre; Moustafa, Julia El-Sayed; Menni, Cristina; Steves, Claire J.; Kelsey, Karl; Ling, Charlotte; Grundberg, Elin; Small, Kerrin S. and Bell, Jordana T.
Genome Medicine, 14, Article 75(1)

Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans (2022)
Roberts, Amy L.; Morea, Alessandro; Amar, Ariella; Zito, Antonino; El-Sayed Moustafa, Julia S.; Tomlinson, Max; Bowyer, Ruth C. E.; Zhang, Xinyan; Christiansen, Colette; Costeira, Ricardo; Steves, Claire J.; Mangino, Massimo; Bell, Jordana T.; Wong, Chloe C. Y.; Vyse, Timothy J. and Small, Kerrin S.
eLife, 11, Article e78263

Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects (2021)
Christiansen, C.; Castillo-Fernandez, J. E.; Domingo-Relloso, A.; Zhao, W.; El-Sayed Moustafa, J. S.; Tsai, P.-C.; Maddock, J.; Haack, K.; Cole, S. A.; Kardia, S. L. R.; Molokhia, M.; Suderman, M.; Power, C.; Relton, C.; Wong, A.; Kuh, D.; Goodman, A.; Small, K. S.; Smith, J. A.; Tellez-Plaza, M.; Navas-Acien, A.; Ploubidis, G. B.; Hardy, R. and Bell, J. T.
Clinical Epigenetics, 13(1)

Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study (2021)
Mullins, Edward; Costeira, Ricardo; Lee, Karla A.; Murray, Benjamin; Christiansen, Colette; Castillo-Fernandez, Juan; Ni Lochlainn, Mary; Capdevila Pujol, Joan; Macfarlane, Heather; Kenny, Louise C.; Buchan, Iain; Wolf, Jonathan; Rymer, Janice; Ourselin, Sebastien; Steves, Claire J.; Spector, Timothy D.; Newson, Louise R. and Bell, Jordana T.
PLOS ONE, 16(9) (e0257051)

Bayesian reassessment of the epigenetic architecture of complex traits (2020)
Trejo Banos, Daniel; McCartney, Daniel L.; Patxot, Marion; Anchieri, Lucas; Battram, Thomas; Christiansen, Colette; Costeira, Ricardo; Walker, Rosie M.; Morris, Stewart W.; Campbell, Archie; Zhang, Qian; Porteous, David J.; McRae, Allan F.; Wray, Naomi R.; Visscher, Peter M.; Haley, Chris S.; Evans, Kathryn L.; Deary, Ian J.; McIntosh, Andrew M.; Hemani, Gibran; Bell, Jordana T.; Marioni, Riccardo E. and Robinson, Matthew R.
Nature Communications, 11(1)

Twins and family epigenetic studies of Type 2 Diabetes (2021-08-27)
Christiansen, Colette; Potier, Louis and Bell, Jordana T
In: Li, Shuai and Hopper, John L eds. Twin and Family Studies of Epigenetics. Translational Epigenetics (pp. 105-118)
ISBN : 978-0-12-820951-6 | Publisher : Elsevier