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  2. Dr Claire Batty

Dr Claire Batty

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Professional biography

I am a PDRA in AstrobiologyOU looking at finding evidence of potential life on icy moons using volatile organic compounds (VOCs).

My background is one of variation! I started my career in Osteopathic Medicine which has involved treating patients in both private clinics and the NHS, as well as working with a sporting teams to provide medical care, and teaching a sports massage and rehabilitation diploma.  During this time, I decided to expand my knowledge even further (because obviously I didn’t have enough to do already!) by enrolling on a part time research MSc degree.

I completed my MSc at Cranfield University in Medical Diagnostics and then moved to the Open University (OU) to complete my PhD ‘Use of Volatile Organic Compound (VOC) Profiling in Investigating Diseases of the Gut and Diet Related Conditions’.  This is where my introduction to VOCs blossomed, and I developed skills in thermal desorption (TD), gas chromatography mass spectrometry (GC-MS), and selective ion flow tube mass spectrometry (SIFT-MS) and it has been an ongoing theme ever since. I was involved with ‘The Brilliant Club’ – teaching school age students about my research – which opened my eyes to encouraging under-represented groups in schools to be confident in applying to highly-selective universities.  Standing on a soapbox was also required – by being in the first year group to present at Milton Keynes’ public outreach platform ‘Soapbox Science’ event.

Two further PDRA roles at the OU lead me into VOC analysis using optical fibre technology, 3D printing diagnostic platforms, and organic compound and surface variation analysis using reflectance UV-spectrophotometry.  I also teach as an associate lecturer for the OU on their SK299 module – human biology.

The amazing thing about VOC analysis and the OU is that it has allowed me to cross between different university faculties and groups, and has encouraged local and international collaboration in the UK (Nottingham University, Cranfield University, University of the West of England, Addenbrookes Hospital, Guy’s Hospital Kings College London, Tharos Ltd) and Japan (The University of Kitakyushu), and has now given me the opportunity to use my current expertise to further expand my knowledge into the environment.  Now, as I return from maternity leave, I’m really looking forward to the new challenge!

Publications

Ex vivo detection and quantification of apically extruded volatile compounds and disinfection by-products by SIFT-MS, during chemomechanical preparation of infected root canals (2020-02)
Ioannidis, K.; Batty, C.; Turner, C.; Smith, D.; Deb, S. and Mannocci, F.
Dental Materials, 36(2) (pp. 257-269)


A laboratory study to assess the formation of effluent volatile compounds and disinfection by‐products during chemomechanical preparation of infected root canals and application of activated carbon for their removal (2020)
Ioannidis, K.; Batty, C.; Turner, C.; Smith, D.; Mannocci, F and Deb, S.
International Endodontic Journal ((Early Access))


Sniffing Out Resistance - Rapid Identification of Urinary Tract Infection-Causing Bacteria and their Antibiotic Susceptibility Using Volatile Metabolite Profiles (2019-04-17)
Smart, Amy; de Lacy Costello, Ben; White, Paul; Avison, Matthew; Batty, Claire; Turner, Claire; Persaud, Raj and Ratcliffe, Norman
Journal of Pharmaceutical and Biomedical Analysis, 167 (pp. 59-65)


Nitrate supplementation in thoroughbred racehorses: Addition of beetroot juice to the equine diet and effects on the gut metabolome (2019-03)
Waring, R. H.; Hunter, J. O.; Turner, C.; Batty, C. and Ramzan, P. H. L.
Integrative Food, Nutrition and Metabolism, 6(2) (pp. 1-4)


Modulation of the equine microbiome by pasture and feed supplements: A metabolomics approach (2019)
Snalune, K. L.; Hunter, J. O.; Waring, R. H.; Cauchi, M.; Turner, C. and Batty, C.
Integrative Food, Nutrition and Metabolism, 6(2) (pp. 1-4)


Is food intolerance a factor underlying chronic immunethrombocytopenia (ITP)? (2018-11)
Batty, Claire A.; Hunter, John O.; Woolner, Jenny; Baglin, Trevor and Turner, Claire
British Journal of Haematology, 183(4) (pp. 683-686)


Differences in microbial metabolites in urine headspace of subjects with Immune Thrombocytopenia (ITP) detected by volatile organic compound (VOC) analysis and metabolomics (2016-10-01)
Batty, Claire A.; Cauchi, Michael; Hunter, J. O.; Woolner, Jenny; Baglin, Trevor and Turner, Claire
Clinica Chimica Acta, 461 (pp. 61-68)


Characterisation of the faecal metabolome and microbiome of Thoroughbred racehorses (2015-09)
Proudman, C. J.; Hunter, J. O.; Darby, A. C.; Escalona, E. E.; Batty, C. and Turner, C.
Equine Veterinary Journal, 47(5) (pp. 580-586)


Use of the analysis of the volatile faecal metabolome in screening for colorectal cancer (2015-06-18)
Batty, Claire A.; Cauchi, Michael; Lourenco, Celia; Hunter, John O. and Turner, Claire
PLoS ONE, 10, Article e0130301(6)


The use of SIFT-MS in profiling the faecal volatile metabolome in horses with colic: a pilot study (2013-10)
Turner, Claire; Batty, Claire; Escalona, Ebony; Hunter, John O. and Proudman, Christopher
Current Analytical Chemistry, 9(4) (pp. 614-621)


Co-ordinated UV Reflectance and Raman Spectroscopy of Martian Meteorites and Terrestrial Analogue Samples (2019)
Grady, Monica; Abernethy, Feargus; Barrett, Thomas; Batty, Claire; Bedford, Candice and Rowden, Pam
In : 82nd Annual Meeting of the Meteoritical Society (7-12 Jul 2019, Sapporo, Japan)