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Description
Shot of an electric probe being inserted into a human scalp. Steven Rose holds one of these probing electrodes. Two others have been inserted into his scalp. Rose sums up the experiments which were... done in programme 1 and then explains what will be done in this programme stimulation of a sensory nerve to the brain. Rose introduces Ivor Gartside. Ivor Gartside shows and explains the apparatus used for this experiment. Rose outlines the experiment. Gartside performs the experiment with Rose as the subject. An oscilloscope registers Rose's response to the electric shock stimulus which he receives. Rose and Gartside discuss the clinical and research purposes and functions of this sort of experiment and equipment. Rose describes the differences between a holistic and a reductionist approach to the study of the brain and nervous system. Shots of an electro-probe being inserted into the brain of a rabbit. Rose shows a recording electrode of the type inserted into the rabbit brain. He then uses a large scale model of the probe to explain how it works. Rose explains how the researcher determines into which part of the brain the probe should be placed. Shots of a standard atlas of laboratory animal brains. Rose explains how these are used to determine the proper position for a probe. Having found the co-ordinates for the desired position, Rose explains how the researcher pinpoints the spot on an actual brain. He uses a rabbit skull to demonstrate how the plane of reference is obtained. Rose describes the apparatus as he demonstrates. Rose with a diagram of a single brain cell. The tip of the recording electrode is shown in the diagram. He explains that this type of recording is extra cellular recording. Rose explains how chemicals which are used during the experiment to stimulate or depress neuron activity are forced out of the multi-barrel recording electrode. The technique of iontophoresis is used. Rose uses an animated diagram to explain how it works. D.W.Straughan demonstrates the techniques of inserting a recording electrode into a rabbit's brain. Once in, he demonstrates the iontophoretis process. The neuron response to glutamate and GABA are monitored. Commentary by Straughan explains the whole procedure. Rose sums up the programme.
Metadata describing this Open University video programme
Module code and title: SDT286, Biological bases of behaviour
Item code: SDT286; 02
First transmission date: 28-01-1972
Published: 1972
Rights Statement:
Restrictions on use:
Duration: 00:23:42
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Producer: John Groom
Contributors: Stephen Rose; Donald Straughan
Publisher: BBC Open University
Keyword(s): Brain stimulation; Extra-cellular recording; Iontophoresis; Neurons; Oscilloscope; Probing electrodes; Rabbit brain; Sensory nerve
Master spool number: 6LT/70437
Production number: 00521_2142
Videofinder number: 2089
Available to public: no