Available online
Description
Sickle cell disease is a heritable disease. This is because the defect causing it resides in the structure of DNA, the hereditary material that is passed on from generation to generation. This pro...gramme uses sickle cell disease as a vehicle to introduce a basic genetic vocabulary and shows how the defect in the DNA, a mutation, gives rise to defective blood protein, haemoglobin, and as a consequence to the symptoms that characterise this disease. Our 20th century understanding of inheritance has been developed by experiments performed on the fruit fly and examples of normal "wild type" male and female flies together with mutant flies are shown and related to genetic analysis and to current research still using the fruit fly, into the problems of development.
Sickle cell disease is a heritable disease. This is because the defect causing it resides in the structure of DNA, the hereditary material that is passed on from generation to generation. This pro...gramme uses sickle cell disease as a vehicle to introduce a basic genetic vocabulary and shows how the defect in the DNA, a mutation, gives rise to defective blood protein, haemoglobin, and as a consequence to the symptoms that characterise this disease. Our 20th century understanding of inheritance has been developed by experiments performed on the fruit fly and examples of normal "wild type" male and female flies together with mutant flies are shown and related to genetic analysis and to current research still using the fruit fly, into the problems of development.
| Module code and title: | S299, Genetics |
|---|---|
| Item code: | S299; 02; 1978 |
| First transmission date: | 22-03-1978 |
| Published: | 1978 |
| Rights Statement: | |
| Restrictions on use: | |
| Duration: | 00:21:39 |
| + Show more... | |
| Producer: | Roger Jones |
| Contributors: | Garard Green; J M White; Robert Whittle |
| Publisher: | BBC Open University |
| Keyword(s): | DNA; Fruit fly; Genotype; Mutations; Phenotype; Sickle cell disease |
| Master spool number: | 6HT/72683 |
| Production number: | 00525_1321 |
| Videofinder number: | 991 |
| Available to public: | no |
