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Description
This programme looks at the synthesis of a single compound which will become a drug.
Metadata describing this Open University video programme
Module code and title: S344, Organic chemistry: a synthesis approach
Item code: S344; 05
First transmission date: 1989
Published: 1989
Rights Statement:
Restrictions on use:
Duration: 00:25:00
Note: Loan copy available on compilation video S344/1,2,3,4,5,6
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Producer: Nick Watson
Contributor: Peter Taylor
Publisher: BBC Open University
Keyword(s): Cardio-vascular diseases; Drugs; Glaxo; Heart disease; Laboratory synthesis; Prostaglandins
Subject terms: Prostaglandins; Glaxo;
Footage description: Footage - Arachadonic acid cascade. Leucotrienes. Prostaglandins (0'26"-2'45") - Diagram of AH19437 (4'00"-4'20") - Diagram of thromboxane antagonist. Arachadonic acid cascade (5'21"-5'47") - Diagram of cyclopentadiene (5'48"-6'25") - Model of chiral molecule. Diagram of process of resolution (7'28"-8'25") -Diagram of bicyclic compound (9'28"-10'04") - Model & computer graphic of bromohydrin formation (10'05"-11'41") - Diagram of target molecule (11'42"-12'05") - Diagram of formation of norboranone (12'17"-14'18") - Diagram of tricyclic ketone and its reaction with a nucleophile (14'35"-16'02") - Diagram of regioselective reaction. 'Ball & stick' graphic. Diagram of prostaglandin D2 (16'03"-17'48") - Fume cupboard. Synthesis machinery (17'49"-18'18") - Diagram of AH23848 & AN32191 (18'51"-20'27") - Model of arachadonic acid cascade (20'28"-20'55").
Master spool number: HOU6238
Production number: FOUS559K
Videofinder number: 3020
Available to public: no