Programme examines cell membrane structure with the aid of models.
Metadata describing this Open University video programme
Module code and title: S321, Physiology of cells and organisms
Item code: S321; 02
First transmission date: 24-02-1974
Published: 1974
Rights Statement:
Restrictions on use:
Duration: 00:24:16
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Producer: Roger Jones
Contributors: Vic Daniels; Hugh Davson
Publisher: BBC Open University
Keyword(s): Artificial membranes; Danielli-Davson model; Freeze-cleaving; Membrane models; Singer-Nicholson model
Footage description: Film shots of amoeba under magnification. CU shot of its cell membrane. Vic Daniels introduces the programme. He gives the chemical composition of a lipid molecule, a major component of cell membrane. Daniels discusses cell membrane structure with the aid of molecular models. He uses mainly lollipop models of membrane lipid molecules which he combines to model the membrane. Hugh Davson, one of the pioneers of cell membrane study, with the Danielli - Davson model of cell membrane. He explains how they arrived at this model. Vic Daniels discusses the effect of the electron microscope on the study of cell membrane. Shots of electron micrographs of a red blood cell membrane and of a Schwann cell. Daniels uses a schematic diagram of a cell membrane cross section to explain Robertson's hypothesis of a universal cell membrane. He then explains the use of X - Ray diffraction in cell membrane study. Daniels explains the freeze cleaving technique for splitting membrane. Shot of electron micrograph showing a freeze cleaved red blood cell membrane. Shots of EM micrograph showing three freeze cleaved red blood cell membranes. Daniels compares them. In two cases the membrane were treated with pronase and marked differences are seen. Daniels explains what this tells about the nature of cell membranes. Daniels with the most recent model of cell membrane structure. He points out and explains the components. H. Davson gives a critique of this model, all the time. Daniels introduces Lindsey Gordon. Lindsey Gordon discusses his work with artifcial membranes. He explains how a lipid bi-layer film is obtained in the lab. An animated diagram aids. Gordon explains how electric charges can pass through a bi-layer film which is normally impervious to electric charges. He uses animated diagrams and graphs as aids. Vic Daniels sums up.
Master spool number: 6HT/71164
Production number: 00525_1107
Videofinder number: 1819
Available to public: no