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Description
The chemical problem with Thalidomide and how the drug industry worked to solve the problem.
The chemical problem with Thalidomide and how the drug industry worked to solve the problem.
| Module code and title: | S344, Organic chemistry: a synthesis approach |
|---|---|
| Item code: | S344; 03 |
| First transmission date: | 1989 |
| Published: | 1989 |
| Rights Statement: | |
| Restrictions on use: | |
| Duration: | 00:25:00 |
| Note: | Loan copy available on compilation video S344/1,2,3,4,5,6. |
| + Show more... | |
| Producer: | Nick Watson |
| Contributor: | David Roberts |
| Publisher: | BBC Open University |
| Keyword(s): | Chirality; Synthesis; Thalidomide |
| Subject terms: | Chiral drugs--Synthesis |
| Footage description: | Footage - Graphic of thalidomide molecular structure. Film of thalidomide children (1'32"-2'07") - Pine forest (4'02"-4'25") - Graphic of alpine-borane isomers (4'58"-5'50") - Computer graphic of S isomer and R isomer transition states (5'51"-6'49") - Graphic of alpine-borane & di-iso-pino-camphenyl-chloro-borane (Ipc2BCI) molecular structure (6'50"-7'24") - Graphic of reduction of acetophenone (8'00"-8'17") - Graphic of Ipc2BCI and alpine-borane. Computer graphic of chiral iron acyl (8'59"-9'45") - Computer graphic of chiral iron acyl reagent (10'37"-13'04") - Graphic of generation of new chiral centre (13'29"-14'06") - Graphic of stereochemistry of chiral centre (14'33"-14'42") - Graphic of nucleophilic attack (15'48"-16'42") - Graphic of homochiral molecule synthesis (17'52"-18'21") - Graphic of self-racemisation in the reaction medium (19'08"-19'36"). |
| Master spool number: | HOU6262 |
| Production number: | FOUS562S |
| Videofinder number: | 3005 |
| Available to public: | no |
